BDBM109236 WEHI-539

SMILES NCc1ccc(OCCCc2sc(nc2C(O)=O)-c2ccc3CCCC(=NNc4nc5ccccc5s4)c3c2)cc1

InChI Key InChIKey=JKMWZKPAXZBYEH-UHFFFAOYSA-N

Data  6 IC50  4 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109236   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Walter and Eliza Hall Institute of Medical Research

LigandPNGBDBM109236(WEHI-539)
Affinity DataIC50: >1.20E+4nM Kd: >750nMpH: 7.4Assay Description:The protocols for tight and weak binders were described in Biacore S51 assay set-up with a flow rate of 30 µL/min. For His-Bcl-2 protein assays...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed